Next-Generation Sequencing technologies (NGS) are trasforming today's biology by making it economically feasible to read the complete genome of individuals. Single nucleotide polymorphism (SNP) is the most common form of individual DNA variation; and the set of SNPs present in a chromosome (called the haplotype) is of interest in a wide area of applications in molecular biology and biomedicine. Personalized haplotyping of (portions of/all) the chromosomes of individuals through NGS is one of themost promising basic ingredients leading
ReHap: A framework for single individual haplotyping from next-generation sequencing data
Geraci F;Pellegrini M
2011
Abstract
Next-Generation Sequencing technologies (NGS) are trasforming today's biology by making it economically feasible to read the complete genome of individuals. Single nucleotide polymorphism (SNP) is the most common form of individual DNA variation; and the set of SNPs present in a chromosome (called the haplotype) is of interest in a wide area of applications in molecular biology and biomedicine. Personalized haplotyping of (portions of/all) the chromosomes of individuals through NGS is one of themost promising basic ingredients leadingFile in questo prodotto:
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