The fungal pathogen Fusarium culmorum causes Fusarium head blight (FHB) on cereals resulting in yield loss and contamination of grain with type B trichotecene mycotoxins such as deoxynivalenol (DON), and its acetylated derivatives. A key step in the synthesis of trichothecenes is catalyzed by the trichodiene synthase 5 (TRI5) that converts farnesyl pyrophosphate to trichodiene.

Analysis of the interaction of trichodiene synthase 5 (TRI5) with natural and natural-like inhibitors of trichothecene biosyntesis

R Dallocchio;G Delogu
2016

Abstract

The fungal pathogen Fusarium culmorum causes Fusarium head blight (FHB) on cereals resulting in yield loss and contamination of grain with type B trichotecene mycotoxins such as deoxynivalenol (DON), and its acetylated derivatives. A key step in the synthesis of trichothecenes is catalyzed by the trichodiene synthase 5 (TRI5) that converts farnesyl pyrophosphate to trichodiene.
2016
Istituto di Chimica Biomolecolare - ICB - Sede Pozzuoli
Fusarium culmorum Modeling DON TRI5
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/316983
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