Autophagy is a self-digestive process regulated by an intricate network of factors able either to ensure the pro-survival function of autophagy or to convert it in a death pathway. Recently, the involvement of microRNAs in the regulation of autophagy networks has been reported. This review will summarize the main features of these small non-coding endogenous RNAs, focusing on their relevance in cancer and finally addressing their impact on autophagy.
Autophagy is a self-digestive process regulated by an intricate network of factors able either to ensure the prosurvival function of autophagy or to convert it in a death pathway. Recently, the involvement of miRNAs in the regulation of autophagy networks has been reported. This review will summarize the main features of these small noncoding endogenous RNAs, focusing on their relevance in cancer and finally addressing their impact on autophagy.
A new function for miRNAs as regulators of autophagy
2017
Abstract
Autophagy is a self-digestive process regulated by an intricate network of factors able either to ensure the prosurvival function of autophagy or to convert it in a death pathway. Recently, the involvement of miRNAs in the regulation of autophagy networks has been reported. This review will summarize the main features of these small noncoding endogenous RNAs, focusing on their relevance in cancer and finally addressing their impact on autophagy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
