Micro-Abstract We use the mass spectrometry technique for the detection of circulating peptides in patients with familial adenomatous polyposis (FAP). We describe a FAP-specific fingerprint that allows early identification of the disease and neoplastic transformation. Our results are relevant because they could postpone preventive surgery as long as possible, improving the quality of life of patients with FAP.

Peptide Patterns as Discriminating Biomarkers in Plasma of Patients With Familial Adenomatous Polyposis

Traldi P;
2016

Abstract

Micro-Abstract We use the mass spectrometry technique for the detection of circulating peptides in patients with familial adenomatous polyposis (FAP). We describe a FAP-specific fingerprint that allows early identification of the disease and neoplastic transformation. Our results are relevant because they could postpone preventive surgery as long as possible, improving the quality of life of patients with FAP.
2016
Istituto di Chimica della Materia Condensata e di Tecnologie per l'Energia - ICMATE
Circulating plasma peptides
Colon cancer
Complement system C3f
Matrix-assisted laser desorption/ionization
Switch adenoma-carcinoma
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/327361
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