A new technique, exploiting magnetic nanoparticles as contrast agent, has been recently proposed for microwave breast cancer imaging. As human tissues are non magnetic, the adoption of a magnetic contrast agent, able to selectively target tumoral cells, represents an effective means to increase diagnostic reliability. Although the effectiveness of the new technique has been fully assessed through realistic and accurate numerical simulations, an experimental proof-of-concept is still needed to set the ground for a subsequent pre-clinical stage. In this communication, we present the first results of such an experimental validation, performed with an ad hoc designed laboratory set-up and exploiting a realistic (although simplified) breast phantom.
Experimental feasibility assessment of MNP enhanced microwave diagnostics of breast cancer
Bucci Ovidio M;Bellizzi Gennaro;Crocco Lorenzo;Scapaticci Rosa
2016
Abstract
A new technique, exploiting magnetic nanoparticles as contrast agent, has been recently proposed for microwave breast cancer imaging. As human tissues are non magnetic, the adoption of a magnetic contrast agent, able to selectively target tumoral cells, represents an effective means to increase diagnostic reliability. Although the effectiveness of the new technique has been fully assessed through realistic and accurate numerical simulations, an experimental proof-of-concept is still needed to set the ground for a subsequent pre-clinical stage. In this communication, we present the first results of such an experimental validation, performed with an ad hoc designed laboratory set-up and exploiting a realistic (although simplified) breast phantom.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.