The application of intense, short-duration pulsed electric fields to mammalian cells causes an increase in the permeability of plasma membrane to external molecules (electroporation). Electroporation-based technologies find application in biomedical, industrial and environmental fields, but fundamental interactions between biological structures and electric field remain to be elucidated. In this presentation, the potentiality of Terahertz spectroscopy in sensing the modification at the plasma membrane level under electroporation will be discussed. Preliminary results of time-domain THz spectroscopy of human monocyte samples exposed to 8, 100 µs long, 1 kV/cm pulsed electric fields were also presented
TeraHertz Spectroscopy for Electroporation
Romeo S
2017
Abstract
The application of intense, short-duration pulsed electric fields to mammalian cells causes an increase in the permeability of plasma membrane to external molecules (electroporation). Electroporation-based technologies find application in biomedical, industrial and environmental fields, but fundamental interactions between biological structures and electric field remain to be elucidated. In this presentation, the potentiality of Terahertz spectroscopy in sensing the modification at the plasma membrane level under electroporation will be discussed. Preliminary results of time-domain THz spectroscopy of human monocyte samples exposed to 8, 100 µs long, 1 kV/cm pulsed electric fields were also presentedI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
