Synthesis and evaluation of gold nanoparticle-modified polyelectrolyte capsules under microwave irradiation for remotely controlled release for cargo

The Layer-by-Layer fabrication of polyelectrolyte capsules with and without Au nanoparticles embedded into their walls is reported. We have studied the behaviour of these capsules under microwave irradiation. Their properties have been investigated by transmission electron microscopy and dynamic light scattering measurements. We demonstrate that microwaves affect the structure of both capsules types by inducing remarkable damage to the multilayer wall. We also show that upon microwave exposure the walls of polyelectrolyte capsules which are modified with Au nanoparticles undergo rapid damage compared to capsules without incorporated nanoparticles. These results indicate that microwaves can be used to control the opening of cargo-loaded capsules, which could be harnessed for drug delivery purposes. © 2011 The Royal Society of Chemistry.