Bovine BAC clones containing the 31 type I Texas markers earlier used to definitively assign the 31 bovine syntenic groups (U) to cattle chromosomes, were comparatively FISH-mapped to sheep and goat R-banded chromosomes according to ISCNDB2000. All 31 type I markers were localized on homoeologous chromosomes and chromosome bands of the two species in agreement with previous localizations obtained both in cattle and river buffalo, definitively confirming chromosome homoeologies between Caprinae and Bovinae. In addition, we have extended physical maps of sheep and goat since 11 type I loci (HSD3B1, INHBA, CSN10, IGF2R, PIGR, MAP1B, DSC1, ELN, TNFRSF6, CGN1, IGF2) and 14 type I loci (SOD1, HSD3B1, CSN10, IGF2R, RB1, TG, PIGR, MAP1B, IGH@, LTF, DSC1, TNFRSF6, CGN1 and IGF2) were assigned for the first time to goat and sheep chromosomes, respectively.
Chromosome localization of the 31 type I Texas bovine markers in sheep and goat chromosomes by comparative FISH-mapping and R-banding
Di Meo GP;Perucatti A;Incarnato D;Iannuzzi L
2003
Abstract
Bovine BAC clones containing the 31 type I Texas markers earlier used to definitively assign the 31 bovine syntenic groups (U) to cattle chromosomes, were comparatively FISH-mapped to sheep and goat R-banded chromosomes according to ISCNDB2000. All 31 type I markers were localized on homoeologous chromosomes and chromosome bands of the two species in agreement with previous localizations obtained both in cattle and river buffalo, definitively confirming chromosome homoeologies between Caprinae and Bovinae. In addition, we have extended physical maps of sheep and goat since 11 type I loci (HSD3B1, INHBA, CSN10, IGF2R, PIGR, MAP1B, DSC1, ELN, TNFRSF6, CGN1, IGF2) and 14 type I loci (SOD1, HSD3B1, CSN10, IGF2R, RB1, TG, PIGR, MAP1B, IGH@, LTF, DSC1, TNFRSF6, CGN1 and IGF2) were assigned for the first time to goat and sheep chromosomes, respectively.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
