Excitation spectra overlap between fluorescence indicators and optogenetic tools limits the development of an all-optical system for neural circuits interrogation. Here we describe how we solved the puzzle by combining red-shifted GECI with Channelrhodopsin 2.

All-optical simultaneous stimulation and readout of motor cortex activity in Awake Mice

Resta F;Conti E;Sacconi L;Allegra Mascaro AL;Pavone FS
2018

Abstract

Excitation spectra overlap between fluorescence indicators and optogenetic tools limits the development of an all-optical system for neural circuits interrogation. Here we describe how we solved the puzzle by combining red-shifted GECI with Channelrhodopsin 2.
2018
Istituto di Neuroscienze - IN -
All-optical systems
Excitation spectrum
Fluorescence indicators
Motor cortex
Neural circuits
Red-shifted
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/348277
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