Hensman Moss DJ, Pardiñas AF, Langbehn D, et al. Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study. Lancet Neurol 2017; published online June 19. http://dx.doi.org/10.1016/S1474-4422(17)30161-8--In the appendix of this article, some of the members of the Track Investigator list were not listed. This correction has been made in the online version as of June 28, 2017. Huntington's disease is caused by a CAG repeat expansion in the huntingtin gene, HTT. Age at onset has been used as a quantitative phenotype in genetic analysis looking for Huntington's disease modifiers, but is hard to define and not always available. Therefore, we aimed to generate a novel measure of disease progression and to identify genetic markers associated with this progression measure.
Corrections: Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study (The Lancet Neurology (2017) 16(9) (701-711) (S1474442217301618) (10.1016/S1474-4422(17)30161-8))
2017
Abstract
Hensman Moss DJ, Pardiñas AF, Langbehn D, et al. Identification of genetic variants associated with Huntington's disease progression: a genome-wide association study. Lancet Neurol 2017; published online June 19. http://dx.doi.org/10.1016/S1474-4422(17)30161-8--In the appendix of this article, some of the members of the Track Investigator list were not listed. This correction has been made in the online version as of June 28, 2017. Huntington's disease is caused by a CAG repeat expansion in the huntingtin gene, HTT. Age at onset has been used as a quantitative phenotype in genetic analysis looking for Huntington's disease modifiers, but is hard to define and not always available. Therefore, we aimed to generate a novel measure of disease progression and to identify genetic markers associated with this progression measure.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
