An inverse diffusion problem that appears in Magnetic Resonance dosimetry is studied. The problem is shown to be equivalent to a deconvolution problem with a known kernel. To cope with the singularity of the kernel, nonlinear regularization functionals are considered which can provide regular solutions, reproduce steep gradients and impose positivity constraints. A fast deterministic algorithm for solving the involved non-convex minimization problem is used. Accurate restorations on real 256×256 images are obtained by the algorithm in a few minutes on a 266-MHz PC that allow to precisely quantitate the relative absorbed dose.

Solving an inverse diffusion problem for Magnetic Resonance dosimetry by a fast regularization method

Barone P;Sebastiani G
2001

Abstract

An inverse diffusion problem that appears in Magnetic Resonance dosimetry is studied. The problem is shown to be equivalent to a deconvolution problem with a known kernel. To cope with the singularity of the kernel, nonlinear regularization functionals are considered which can provide regular solutions, reproduce steep gradients and impose positivity constraints. A fast deterministic algorithm for solving the involved non-convex minimization problem is used. Accurate restorations on real 256×256 images are obtained by the algorithm in a few minutes on a 266-MHz PC that allow to precisely quantitate the relative absorbed dose.
2001
Istituto Applicazioni del Calcolo ''Mauro Picone''
diffusion
magnetic resonance
inverse problems
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/353327
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