We investigated the presence of anti-HLA antibodies and the distribution of lymphocyte subpopulations in 77 kidney-transplanted children and young adults compared to 23 healthy controls. Moreover, we tested whether the presence of anti-HLA antibodies could be related to modification in lymphocyte phenotype. Finally, we correlated the presence of anti-HLA antibodies and specific alteration of lymphocyte subsets with clinical outcomes.
In the field of kidney transplantation, identifying early signatures of humoral rejection is a key challenge.
Cellular immune profile of kidney transplant patients developing anti-HLA antibodies during childhood
Piazza Antonina;
2016
Abstract
In the field of kidney transplantation, identifying early signatures of humoral rejection is a key challenge.File in questo prodotto:
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