We propose a fabrication technique for the fast and cheap production of 3D replicas of proteins. We leverage silicone casting with rigid molds, to produce flexible models which can be safely extracted from the mold, and easily manipulated to simulate the biological interaction mechanisms between proteins. We believe that tangible models can be useful in education as well as in laboratory settings, and that they will ease the understanding of fundamental principles of macromolecular organization.

Computational fabrication of macromolecules to enhance perception and understanding of biological mechanisms

Alderighi T.;Giorgi D.;Malomo L.;Cignoni P.;Zoppe' M.
2019

Abstract

We propose a fabrication technique for the fast and cheap production of 3D replicas of proteins. We leverage silicone casting with rigid molds, to produce flexible models which can be safely extracted from the mold, and easily manipulated to simulate the biological interaction mechanisms between proteins. We believe that tangible models can be useful in education as well as in laboratory settings, and that they will ease the understanding of fundamental principles of macromolecular organization.
2019
Istituto di Biofisica - IBF
Istituto di Scienza e Tecnologie dell'Informazione "Alessandro Faedo" - ISTI
978-3-03868-100-7
Marcomolecules
Digital Fabrication
Fabrication
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/361087
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