Robotic training combined with transient contralesional inactivation was recently shown to promote a generalized recovery after stroke. Here, Allegra Mascaro et al. investigate how this rehabilitation paradigm affects neuronal and vascular plasticity of the mouse cortex. Synaptic stabilization is associated with angiogenesis and recovery of a segregated motor representation.

Combined Rehabilitation Promotes the Recovery of Structural and Functional Features of Healthy Neuronal Networks after Stroke

Allegra Mascaro AL
Co-primo
;
Spalletti C;Alia C;Sacconi L;Caleo M;Pavone FS
Ultimo
2019

Abstract

Robotic training combined with transient contralesional inactivation was recently shown to promote a generalized recovery after stroke. Here, Allegra Mascaro et al. investigate how this rehabilitation paradigm affects neuronal and vascular plasticity of the mouse cortex. Synaptic stabilization is associated with angiogenesis and recovery of a segregated motor representation.
2019
Istituto di Neuroscienze - IN -
Istituto Nazionale di Ottica - INO
angiogenesis
calcium imaging
cerebral cortex. in vivo
optogenetics
pharmacological therapy
photothrombosis
robotic rehabilitation
spine plasticity
two-photon microscopy
File in questo prodotto:
File Dimensione Formato  
prod_414752-doc_162582.pdf

accesso aperto

Descrizione: Combined Rehabilitation Promotes the Recoveryof Structural and Functional Features
Tipologia: Versione Editoriale (PDF)
Licenza: Creative commons
Dimensione 3.82 MB
Formato Adobe PDF
3.82 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/362701
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 43
  • ???jsp.display-item.citation.isi??? 39
social impact