All of us know very well the importance of the catalysis in organic synthesis. Catalyzed reactions are usually preferred when planning a new synthetic approach and the choice of the proper catalyst is of pivotal relevance. In this context, the use of biocatalysts in organic synthesis has grown steadily during the last fifty years. Presently, chemists have become accustomed to the idea that the use of enzymes is essential in a modern synthetic laboratory. It does not matter if a given transformation is performed using whole cell microorganisms or using an isolated enzyme. In both cases, the specific activity and selectivity of one or more enzymes is exploited. In fact, biocatalysts allow for performing a number of chemical reactions with high regio- and stereoselectivity and a large number of biocatalyzed industrial processes have already been established. This Special Issue has been planned in order to collect studies focused on the exploitation of enzyme stereoselectivity for the synthesis of relevant chemicals, such as innovative materials, active pharmaceutical ingredients, natural products, flavours and fragrances, and any other kind of bioactive compounds. Overall, the Special

Enzyme-mediated stereoselective synthesis

Serra S
2019

Abstract

All of us know very well the importance of the catalysis in organic synthesis. Catalyzed reactions are usually preferred when planning a new synthetic approach and the choice of the proper catalyst is of pivotal relevance. In this context, the use of biocatalysts in organic synthesis has grown steadily during the last fifty years. Presently, chemists have become accustomed to the idea that the use of enzymes is essential in a modern synthetic laboratory. It does not matter if a given transformation is performed using whole cell microorganisms or using an isolated enzyme. In both cases, the specific activity and selectivity of one or more enzymes is exploited. In fact, biocatalysts allow for performing a number of chemical reactions with high regio- and stereoselectivity and a large number of biocatalyzed industrial processes have already been established. This Special Issue has been planned in order to collect studies focused on the exploitation of enzyme stereoselectivity for the synthesis of relevant chemicals, such as innovative materials, active pharmaceutical ingredients, natural products, flavours and fragrances, and any other kind of bioactive compounds. Overall, the Special
2019
Istituto di Chimica del Riconoscimento Molecolare - ICRM - Sede Milano
green chemistry
stereoselective synthesis
enzyme
biocatalysis
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/364303
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