Sessa et al. describe SETD5 as a crucial epigenetic enzyme to guarantee the open chromatin state in transcribed gene bodies. This is fundamental for executing correct RNA elongation and transcriptional splicing. These molecular events ensure correct brain development and functioning.
SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring
Broccoli V
2019
Abstract
Sessa et al. describe SETD5 as a crucial epigenetic enzyme to guarantee the open chromatin state in transcribed gene bodies. This is fundamental for executing correct RNA elongation and transcriptional splicing. These molecular events ensure correct brain development and functioning.File in questo prodotto:
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