A full ODE model for the transmission of cholera is investigated, includ- ing both direct and indirect transmission and a nonlinear growth for pathogens. The direct problem is preliminarily studied and characterized in terms of reproduction number, endemic and disease free equilibria. The inverse problem is then discussed in view of parameter estimation and model identification via a Least Squares Approximation approach. The procedure is applied to real data coming from the recent Yemen cholera outbreak of 2017-2018.

Identification of epidemiological models: the case study of Yemen cholera outbreak

MFCarfora;I Torcicollo
2020

Abstract

A full ODE model for the transmission of cholera is investigated, includ- ing both direct and indirect transmission and a nonlinear growth for pathogens. The direct problem is preliminarily studied and characterized in terms of reproduction number, endemic and disease free equilibria. The inverse problem is then discussed in view of parameter estimation and model identification via a Least Squares Approximation approach. The procedure is applied to real data coming from the recent Yemen cholera outbreak of 2017-2018.
2020
Istituto per le applicazioni del calcolo - IAC - Sede Secondaria Napoli
Waterborne disease; inverse problems; differ
File in questo prodotto:
File Dimensione Formato  
Identification of epidemiological models the case study of Yemen cholera outbreak.pdf

solo utenti autorizzati

Tipologia: Versione Editoriale (PDF)
Licenza: NON PUBBLICO - Accesso privato/ristretto
Dimensione 1.63 MB
Formato Adobe PDF
1.63 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/368296
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 13
  • ???jsp.display-item.citation.isi??? 12
social impact