In this work, three different pure inorganic zeolite membranes and three hybrid PLA-containing Mixed Matrix Membranes (MMMs) were fabricated and compared with each other in virtue of their ability to interact with cells for in vitro test applications. Additionally, we report their performances in cell experiments of novel olive oil-containing cosmetics by using two cell lines with (MCF-10A) epithelial and (MCF-7) epithelial-like cancer characteristics. Our in vitro results revealed that all zeolite scaffolds permit to obtain higher cell densities compared to pure polymeric scaffolds. We also describe that epithelial cells preferentially adhere on pure membranes according to decreasing order: Linde type L>Fe-S-1>Fe-ZSM-5. Moreover, we evidenced an opposite behavior of cancer cells that prefer to adhere and growth on MMM scaffolds. This study shows that the anticancer characteristics of novel cosmetics of natural origin can be easily determined and emphasized using zeolite membranes.
Assessment of potential cancer protection of cosmetic products of agro-food origin by Zeolite Scaffolds
Adalgisa Tavolaro;
2018
Abstract
In this work, three different pure inorganic zeolite membranes and three hybrid PLA-containing Mixed Matrix Membranes (MMMs) were fabricated and compared with each other in virtue of their ability to interact with cells for in vitro test applications. Additionally, we report their performances in cell experiments of novel olive oil-containing cosmetics by using two cell lines with (MCF-10A) epithelial and (MCF-7) epithelial-like cancer characteristics. Our in vitro results revealed that all zeolite scaffolds permit to obtain higher cell densities compared to pure polymeric scaffolds. We also describe that epithelial cells preferentially adhere on pure membranes according to decreasing order: Linde type L>Fe-S-1>Fe-ZSM-5. Moreover, we evidenced an opposite behavior of cancer cells that prefer to adhere and growth on MMM scaffolds. This study shows that the anticancer characteristics of novel cosmetics of natural origin can be easily determined and emphasized using zeolite membranes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.