In the last years, the main trends in Analytical Chemistry have been focused on the development of miniaturised techniques. Those allow simplifying the procedures that are carried out in the field, as well as reducing the time consumed and decreasing their environmental impact by the reduction of the amount of toxic organic solvents, other hazards reagents and materials applied. Regarding separation techniques, nano-liquid chromatography (nano-LC) has been considered a very important alternative to conventional liquid chromatography (LC) systems in which the consumption of solvents is still quite high despite the important effort carried out in this sense. In this technique, developed by Karlsson and Novothy in 1988, the separation of the analytes is achieved into capillary columns with smaller internal diameters than 100 pm and eluted at very low mobile phase flows in the range 50-800 nL/min.
A NEW APPROACH FOR PRACTICAL INITIATION OF POSTGRADUATE STUDENTS IN NANOCHROMATOGRAPHY
G D'Orazio;
2019
Abstract
In the last years, the main trends in Analytical Chemistry have been focused on the development of miniaturised techniques. Those allow simplifying the procedures that are carried out in the field, as well as reducing the time consumed and decreasing their environmental impact by the reduction of the amount of toxic organic solvents, other hazards reagents and materials applied. Regarding separation techniques, nano-liquid chromatography (nano-LC) has been considered a very important alternative to conventional liquid chromatography (LC) systems in which the consumption of solvents is still quite high despite the important effort carried out in this sense. In this technique, developed by Karlsson and Novothy in 1988, the separation of the analytes is achieved into capillary columns with smaller internal diameters than 100 pm and eluted at very low mobile phase flows in the range 50-800 nL/min.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
