Madin-Darby bovine kidney cells, which are known to be responsive to the effect of dioxin, have to been used to investigate if exposure to the 2,3,7,8- tetrachlorodibenzo-p-dioxin could alter their membrane currents. Herein, we present preliminary results showing that this chemical modifies ionic membrane currents and that the modification mainly involves the chloride current component.

Membrane Currents in Madin-Darby Bovine Kidney Cells are Enhanced by Exposure to Dioxin

Silvia Santillo;
2019

Abstract

Madin-Darby bovine kidney cells, which are known to be responsive to the effect of dioxin, have to been used to investigate if exposure to the 2,3,7,8- tetrachlorodibenzo-p-dioxin could alter their membrane currents. Herein, we present preliminary results showing that this chemical modifies ionic membrane currents and that the modification mainly involves the chloride current component.
2019
Istituto di Scienze Applicate e Sistemi Intelligenti "Eduardo Caianiello" - ISASI
MDBK
Voltage-gated ion channels
TCDD
Whole cell patch-clamp
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/388034
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