Tbx5 is a key gene involved in heart/limb development. Tbx5 mutations cause Holt-Oram syndrome (HOS) in humans, which is characterized by upper limb malformations and congenital heart defects (CHDs) with an incidence of 1:100000 births.

Role of miR-182 in zebrafish and mouse models of Holt-Oram syndrome

Guzzolino E;D'aurizio R;Mercatanti A;Pitto L
2016

Abstract

Tbx5 is a key gene involved in heart/limb development. Tbx5 mutations cause Holt-Oram syndrome (HOS) in humans, which is characterized by upper limb malformations and congenital heart defects (CHDs) with an incidence of 1:100000 births.
2016
microRNA
miRNA
zebrafish
Holt-Horam syndrome
heart
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/391771
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