Tbx5 is a key gene involved in heart/limb development. Tbx5 mutations cause Holt-Oram syndrome (HOS) in humans, which is characterized by upper limb malformations and congenital heart defects (CHDs) with an incidence of 1:100000 births.
Role of miR-182 in zebrafish and mouse models of Holt-Oram syndrome
Guzzolino E;D'aurizio R;Mercatanti A;Pitto L
2016
Abstract
Tbx5 is a key gene involved in heart/limb development. Tbx5 mutations cause Holt-Oram syndrome (HOS) in humans, which is characterized by upper limb malformations and congenital heart defects (CHDs) with an incidence of 1:100000 births.File in questo prodotto:
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