So far, most of the treatment strategies for AD have been direct to lower total Aβ levels in the brain and have failed dramatically [7] The awareness that there is a pool of functional Aβ has led to on-going attempts (e.g., with aducanumab) to rebalance Aβ levels rather than reduce them strictly.

A promising connection between BDNF and Alzheimer's disease

Giuffrida Maria Laura
Primo
;
Copani Agata;Rizzarelli Enrico
Ultimo
2018

Abstract

So far, most of the treatment strategies for AD have been direct to lower total Aβ levels in the brain and have failed dramatically [7] The awareness that there is a pool of functional Aβ has led to on-going attempts (e.g., with aducanumab) to rebalance Aβ levels rather than reduce them strictly.
2018
Istituto di Biostrutture e Bioimmagini - IBB - Sede Napoli
Istituto di Cristallografia - IC
nerve growth factor
CREB
BDNF
copper and zinc
Abeta monomers
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/393425
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