transcription pathway and its regulatory factors microRNA-132 (miR-132) and Methyl CpG-binding protein 2 (MeCP2).Conclusions: The DF3016A molecule could play a crucial roleas a neuroprotector in the neuroinflammatory insult and nociception by the BDNF transcription pathway activation.The process involves methyl CpG-binding protein 2 (MeCP2)and microRNA-132 (miR-132) regulatory factors, both involved in neuroinflammation and pain modulation.
The c5aR antagonist DF3016a protects neurons from neuroinflammation by increasing BDNF transcription.
Pierluigi Sebastiani;Alessia Colanardi;Silvia Di Loreto
2020-01-01
Abstract
transcription pathway and its regulatory factors microRNA-132 (miR-132) and Methyl CpG-binding protein 2 (MeCP2).Conclusions: The DF3016A molecule could play a crucial roleas a neuroprotector in the neuroinflammatory insult and nociception by the BDNF transcription pathway activation.The process involves methyl CpG-binding protein 2 (MeCP2)and microRNA-132 (miR-132) regulatory factors, both involved in neuroinflammation and pain modulation.File in questo prodotto:
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