Fossati et al. show that, in stark contrast to other iGluRs, the glutamate receptor delta-1 (GluD1) operates at inhibitory, rather than excitatory, synapses in the cortex. GluD1 mediates trans-synaptic signaling governing the formation of synapses between specific interneurons and pyramidal neurons.

Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons

Fossati Matteo;
2019

Abstract

Fossati et al. show that, in stark contrast to other iGluRs, the glutamate receptor delta-1 (GluD1) operates at inhibitory, rather than excitatory, synapses in the cortex. GluD1 mediates trans-synaptic signaling governing the formation of synapses between specific interneurons and pyramidal neurons.
2019
Istituto di Neuroscienze - IN -
adhesion molecule
cerebellin
cortical circuits
gephyrin
glutamate receptor delta-1
inhibitory synapse
synapse specificity
synaptic signaling
synaptogenesis
trans-synaptic interaction
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/410681
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