We present an original hybrid microfluidic platform combining deformability cytometry with impedance cytometry. The system is composed by a hyperbolic channel with integrated microelectrodes in a cross-shaped configuration. The high-throughput electro-optical analysis of flowing red blood cells (RBCs) is reported, Preliminary results encourage the use of this platform for label-free biomechanical and bioelectrical single-cell characterization.

A hyperbolic microfluidic impedance chip for deformability cytometry

de Ninno A;Businaro L;
2020

Abstract

We present an original hybrid microfluidic platform combining deformability cytometry with impedance cytometry. The system is composed by a hyperbolic channel with integrated microelectrodes in a cross-shaped configuration. The high-throughput electro-optical analysis of flowing red blood cells (RBCs) is reported, Preliminary results encourage the use of this platform for label-free biomechanical and bioelectrical single-cell characterization.
2020
Single-cell analysis
Deformability cytometry
Multi-modal analysis
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/418038
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