We have tested thin nano roughened Au films produced by pulsed laser deposition for quantitative SERS sensing of the anti-epileptic drug Perampanel within the range of concentrations of therapeutic interest (3 × 10 M-3 × 10 M). We propose a model to elucidate the dependence of the SERS intensity as a function of analyte concentration and contact time between the Au surface and the solution.

On the performance of laser-synthesized, SERS-based sensors for drug detection

Trusso S;
2020

Abstract

We have tested thin nano roughened Au films produced by pulsed laser deposition for quantitative SERS sensing of the anti-epileptic drug Perampanel within the range of concentrations of therapeutic interest (3 × 10 M-3 × 10 M). We propose a model to elucidate the dependence of the SERS intensity as a function of analyte concentration and contact time between the Au surface and the solution.
2020
Adsorption kinetics
Antiepileptic drug
Au nanoparticles
Perampanel
Pulsed laser deposition
Surface Enhanced Raman Spectroscopy
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/419123
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