Peptide-targeting probes tagged with optical imaging and PET reporters may find applications in innovative diagnostic procedures and image-guided surgeries. The reported synthesis procedure is of general applicability to obtain dual imaging probes using fully unprotected moieties with a selective and rapid chemistry based on native chemical ligation.
An innovative approach for the synthesis of dual modality peptide imaging probes based on the native chemical ligation approach
De Rosa LSecondo
;D'Andrea Luca Domenico
Ultimo
2020
Abstract
Peptide-targeting probes tagged with optical imaging and PET reporters may find applications in innovative diagnostic procedures and image-guided surgeries. The reported synthesis procedure is of general applicability to obtain dual imaging probes using fully unprotected moieties with a selective and rapid chemistry based on native chemical ligation.File in questo prodotto:
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