Vapor-phase deposition methods allow the synthesis and engineering of organic and inorganic thin films, with high control on the chemical composition, physical properties, and conformality. In this review, the recent applications of vapor-phase deposition methods such as initiated chemical vapor deposition (iCVD), plasma enhanced chemical vapor deposition (PE-CVD), and atomic layer deposition (ALD), for the encapsulation of active pharmaceutical drugs are reported. The strategies and emergent routes for the application of vapor-deposited thin films on the drug controlled release and for the engineering of advanced release nanostructured devices are presented.

Strategies for Drug Encapsulation and Controlled Delivery Based on Vapor-Phase Deposited Thin Films

Perrotta Alberto;
2018

Abstract

Vapor-phase deposition methods allow the synthesis and engineering of organic and inorganic thin films, with high control on the chemical composition, physical properties, and conformality. In this review, the recent applications of vapor-phase deposition methods such as initiated chemical vapor deposition (iCVD), plasma enhanced chemical vapor deposition (PE-CVD), and atomic layer deposition (ALD), for the encapsulation of active pharmaceutical drugs are reported. The strategies and emergent routes for the application of vapor-deposited thin films on the drug controlled release and for the engineering of advanced release nanostructured devices are presented.
2018
ALD
drug encapsulation
embedding
hydrogel
iCVD
PE-CVD
surface modification
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/423556
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