We performed an epitope mapping based on the "Chemical Reverse Approach", synthesizing 23 overlapping peptides of tTG(1-230) by SPPS. The pentadecapeptides will be useful for RIA, ELISA, and SPR to evaluate the IgA response against tTG specific epitopes in gluten free diet celiac patients' sera.
Celiac disease: synthesis of overlapping linear peptide epitopes of tTG [aa(1-230)].
Giuseppina Sabatino;
2010
Abstract
We performed an epitope mapping based on the "Chemical Reverse Approach", synthesizing 23 overlapping peptides of tTG(1-230) by SPPS. The pentadecapeptides will be useful for RIA, ELISA, and SPR to evaluate the IgA response against tTG specific epitopes in gluten free diet celiac patients' sera.File in questo prodotto:
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