Objectives: To examine serum chitotriosidase activity and YKL-40 levels in patients with asthma and chronic obstructive pulmonary disease (COPD) and evaluate clinically relevant factors that may affect chitinase levels, including genetic variability, corticosteroid treatment, disease exacerbations, and allergen exposure.

Rationale: Serum chitinases may be novel biomarkers of airway inflammation and remodeling, but less is known about factors regulating their levels.

Increased YKL-40 and Chitotriosidase in Asthma and Chronic Obstructive Pulmonary Disease

2016

Abstract

Rationale: Serum chitinases may be novel biomarkers of airway inflammation and remodeling, but less is known about factors regulating their levels.
2016
Istituto di Farmacologia Traslazionale - IFT - Sede Secondaria Palermo
Istituto di biomedicina e di immunologia molecolare - IBIM - Sede Palermo (attivo dal 18/11/1923 al 31/12/2021)
Inglese, Medio (1100-1500)
193
2
131
142
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Objectives: To examine serum chitotriosidase activity and YKL-40 levels in patients with asthma and chronic obstructive pulmonary disease (COPD) and evaluate clinically relevant factors that may affect chitinase levels, including genetic variability, corticosteroid treatment, disease exacerbations, and allergen exposure.
asthma
chitotriosidase
chronic obstructive pulmonary disease
YKL-40
15
info:eu-repo/semantics/article
262
James Anna, J; Reinius Lovisa, E; Marri, Verhoek; Anna, Gomes; Maciej, Kupczyk; Ulf, Hammar; Junya, Ono; Shoichiro, Ohta; Kenji, Izuhara; Elisabeth, B...espandi
01 Contributo su Rivista::01.01 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/426930
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