In this study, the results of 46170 simulations corresponding to the same number of virtual subjects, experiencing different lifestyle conditions, are analysed for the construction of a statistical model able to recapitulate the simulated dynamics.

Investigation about the mechanisms involved in the onset of type 2 diabetes in absence of familiarity is the focus of a research project which has led to the development of a computational model that recapitulates the aetiology of the disease. The model simulates the metabolic and immunological alterations related to type-2 diabetes associated to several clinical, physiological and behavioural characteristics of representative virtual patients.

Potential predictors of type-2 diabetes risk: machine learning, synthetic data and wearable health devices

Stolfi Paola;Palumbo Maria Concetta;Tieri Paolo;Castiglione Filippo
2019

Abstract

Investigation about the mechanisms involved in the onset of type 2 diabetes in absence of familiarity is the focus of a research project which has led to the development of a computational model that recapitulates the aetiology of the disease. The model simulates the metabolic and immunological alterations related to type-2 diabetes associated to several clinical, physiological and behavioural characteristics of representative virtual patients.
2019
Istituto Applicazioni del Calcolo ''Mauro Picone''
In this study, the results of 46170 simulations corresponding to the same number of virtual subjects, experiencing different lifestyle conditions, are analysed for the construction of a statistical model able to recapitulate the simulated dynamics.
T2D
diabetes
mathematical and computational modelling
simulation
machine learning
random forest
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/427424
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