METHODS: Between Jan-2007 and Dec-2014, we enrolled 59 patients with FD unresponsive to first-line therapy with proton pump inhibitors and/or domperidone that underwent OBT before and after 3 months of buspirone (N.=32), amitriptyline (N.=16) or clebopride (N.=11) treatment.
BACKGROUND: Gastric motility is a key-factor in the pathogenesis of functional dyspepsia (FD). C-13-octanoic Acid Breath Test (OBT) is a tool used for measuring gastric emptying time in clinical setting. We aimed to investigate the variation in FD symptoms and OBT parameters after treatment with buspirone, amitriptyline or clebopride.
Gastric emptying and related symptoms in patients treated with buspirone, amitriptyline or clebopride: a "real world" study by C-13-octanoic Acid Breath Test
Fagoonee Sharmila;
2017
Abstract
BACKGROUND: Gastric motility is a key-factor in the pathogenesis of functional dyspepsia (FD). C-13-octanoic Acid Breath Test (OBT) is a tool used for measuring gastric emptying time in clinical setting. We aimed to investigate the variation in FD symptoms and OBT parameters after treatment with buspirone, amitriptyline or clebopride.File in questo prodotto:
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