The results obtained in the present study have demonstrated that these connexins decrease in rat cardiomyocytes and in rat hepatocytes as they age. This change was revealed only at protein level, as connexinmRNAs remained unchanged during aging. Moreover, the aged rats showed an increase in body fat, whose subcutaneous layer tended to be higher.

Heart and liver connexin expression related to the first stage of aging: A study on naturally aged animals

Cabiati Manuela;Panetta Daniele;Burchielli Silvia;Del Ry Silvia;
2020

Abstract

The results obtained in the present study have demonstrated that these connexins decrease in rat cardiomyocytes and in rat hepatocytes as they age. This change was revealed only at protein level, as connexinmRNAs remained unchanged during aging. Moreover, the aged rats showed an increase in body fat, whose subcutaneous layer tended to be higher.
2020
Istituto di Fisiologia Clinica - IFC
Aging
Connexin
Rat
Heart
Liver
Immunohistochemistry
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Descrizione: Heart and liver connexin expression related to the first stage of aging: A study on naturally aged animals
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/429085
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