Effect of cross-slot configuration in microfluidics on o/w emulsification at high throughput

The Liquid-liquid dispersion process is experimentally investigated to manufacture oil-in-water emulsion working at highfowrates in the cross-slot type of microfuidics. Two cross layouts, namely symmetric and asymmetric confgurations, arecompared via characterizing the droplet size and size distribution. Automated granulometry is implemented on the imagestaken by microscopy observations of the emulsion samples. High-speed shadow photography is carried out to discover thecontinuous- and dispersed-phase fow interactions in the vicinity of the collision region. The results show that the designedmicrosystems present great potential in terms of fabricating fne oil droplets distributed in the fnal emulsion. The arithmeticaveraged diameter is less than 10 ?m at all tested fow conditions and the minimum mean diameter reaches 3.9 ?m at the highest energy consumption case. Because of the higher shear stress and more intensifed interaction, the symmetric geometry ofthe cross-slot is benefcial to create fewer amounts of large droplets and dispersing the oil phase more uniformly at the samehydrodynamic conditions, especially in the low Reynolds fow case in this study. As the fowrate is enhanced, the disparitybetween them is diminished due to the instability inside the channel reaching a high level. The mean drop diameter for bothsystems is capable to be scaled with the emulsion velocity-based Weber number. The detrimental efect of the symmetricconfguration is that the energy required to burst the dispersed streams is relatively a little higher than with asymmetric one.