SAveRUNNER is a recently developed network-based tool to efficiently identify novel medical indications for currently approved drugs (known as drug repurposing strategy). Up to now, SAveRUNNER has been gainfully applied to unveil repurposable solutions for several diseases, including viral infection (e.g., SARS, COVID-19, HIV, Malaria, Ebola), breast cancer, progressive disorders of central nervous system (e.g., Amyotrophic Lateral Sclerosis, Multiple Sclerosis), and other neurodegenerative diseases (e.g., Alzheimer's Disease). Here, SAveRUNNER algorithm and its main applications are described. © 2023 Convegno Nazionale di Bioingegneria. All rights reserved.

A network-based algorithm for identifying drug repurposing opportunities for complex diseases

Fiscon G;Conte F;Paci;
2023

Abstract

SAveRUNNER is a recently developed network-based tool to efficiently identify novel medical indications for currently approved drugs (known as drug repurposing strategy). Up to now, SAveRUNNER has been gainfully applied to unveil repurposable solutions for several diseases, including viral infection (e.g., SARS, COVID-19, HIV, Malaria, Ebola), breast cancer, progressive disorders of central nervous system (e.g., Amyotrophic Lateral Sclerosis, Multiple Sclerosis), and other neurodegenerative diseases (e.g., Alzheimer's Disease). Here, SAveRUNNER algorithm and its main applications are described. © 2023 Convegno Nazionale di Bioingegneria. All rights reserved.
2023
Istituto di Analisi dei Sistemi ed Informatica ''Antonio Ruberti'' - IASI
9788855580113
network theory
drug repurposing
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Descrizione: A network-based algorithm for identifying drug repurposing opportunities for complex diseases
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/434865
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