SAveRUNNER is a recently developed network-based tool to efficiently identify novel medical indications for currently approved drugs (known as drug repurposing strategy). Up to now, SAveRUNNER has been gainfully applied to unveil repurposable solutions for several diseases, including viral infection (e.g., SARS, COVID-19, HIV, Malaria, Ebola), breast cancer, progressive disorders of central nervous system (e.g., Amyotrophic Lateral Sclerosis, Multiple Sclerosis), and other neurodegenerative diseases (e.g., Alzheimer's Disease). Here, SAveRUNNER algorithm and its main applications are described. © 2023 Convegno Nazionale di Bioingegneria. All rights reserved.
A network-based algorithm for identifying drug repurposing opportunities for complex diseases
Fiscon G;Conte F;Paci;
2023
Abstract
SAveRUNNER is a recently developed network-based tool to efficiently identify novel medical indications for currently approved drugs (known as drug repurposing strategy). Up to now, SAveRUNNER has been gainfully applied to unveil repurposable solutions for several diseases, including viral infection (e.g., SARS, COVID-19, HIV, Malaria, Ebola), breast cancer, progressive disorders of central nervous system (e.g., Amyotrophic Lateral Sclerosis, Multiple Sclerosis), and other neurodegenerative diseases (e.g., Alzheimer's Disease). Here, SAveRUNNER algorithm and its main applications are described. © 2023 Convegno Nazionale di Bioingegneria. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
