Titan project aims to improve immunotherapy, targeting the efficiency of methods to obtain genetically engineered T cells. Immunotherapy has achieved great success in clinical trials, but it is currently very expensive in terms of time required for analysis, reagents and samples. TITAN aims to the continuous sampling of critical quality attributes, in order to quickly recognize deviations from the desired range and take appropriated corrective actions of process parameters, for an optimal outcome. To achieve its aims, TITAN is currently developing microfluidic and sensing tools for the accurate and efficient real-time monitoring of the T-cells amplification process.
TITAN Project: microfluidic and sensing tools for immunotherapy
Elisabetta Primiceri;Antonio Turco;Valeria Garzarelli;Giulia Siciliano;Alessia Foscarini;Ahmed Alsadig;Benedetta Stampone;Gianluca Trotta;Giuseppe Gigli;Francesco Ferrara
2023
Abstract
Titan project aims to improve immunotherapy, targeting the efficiency of methods to obtain genetically engineered T cells. Immunotherapy has achieved great success in clinical trials, but it is currently very expensive in terms of time required for analysis, reagents and samples. TITAN aims to the continuous sampling of critical quality attributes, in order to quickly recognize deviations from the desired range and take appropriated corrective actions of process parameters, for an optimal outcome. To achieve its aims, TITAN is currently developing microfluidic and sensing tools for the accurate and efficient real-time monitoring of the T-cells amplification process.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
