A stereoselective synthesis of functionalized 2-oxo-1-azabicyclo[5.3.0]alkane is presented. Key events of the synthetic sequence were the stereoselective propenylation of an N-acyliminium ion and a ring-closing metathesis reaction forming a 7-membered lactam.
Stereoselective synthesis of a functionalized 2-oxo-1-azabicyclo[5.3.0]alkane as a potential scaffold for targeted chemotherapy strategieseted chemoterapy strategies
Manzoni L;
2003
Abstract
A stereoselective synthesis of functionalized 2-oxo-1-azabicyclo[5.3.0]alkane is presented. Key events of the synthetic sequence were the stereoselective propenylation of an N-acyliminium ion and a ring-closing metathesis reaction forming a 7-membered lactam.File in questo prodotto:
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Descrizione: Stereoselective synthesis of a functionalized 2-oxo-1-azabicyclo[5.3.0]alkane as a potential scaffold for targeted chemotherapy strategies
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