The selective recognition of caffeine in water among structurally related xanthines and purine or pyrimidine bases was achieved by a simple tweezer-shaped receptor featuring sulfonate hydrosolubilizing groups. The remarkable affinity for caffeine, among the highest reported thus far in the literature and larger than that shown by adenosine receptors of all subtypes, stems from a synergistic combination of hydrogen bonding, CH-pi, and pi-stacking interactions.

A Sulfonated Tweezer-Shaped Receptor Selectively Recognizes Caffeine in Water

Ienco A;
2022

Abstract

The selective recognition of caffeine in water among structurally related xanthines and purine or pyrimidine bases was achieved by a simple tweezer-shaped receptor featuring sulfonate hydrosolubilizing groups. The remarkable affinity for caffeine, among the highest reported thus far in the literature and larger than that shown by adenosine receptors of all subtypes, stems from a synergistic combination of hydrogen bonding, CH-pi, and pi-stacking interactions.
2022
Istituto di Chimica dei Composti OrganoMetallici - ICCOM -
Adenosine receptor; American Chemical Society; Purine basis; Pyrimidine basis; Selective recognition; Simple++; Stacking interaction; Sulphonates; Synergistic combinations
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Descrizione: A Sulfonated Tweezer-Shaped Receptor Selectively Recognizes Caffeine in Water
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/448072
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