Hypertrophic Cardiomyopathies are caused in 60% by mutations in cardiac sarcomere genes (HCM), but also include metabolic diseases, such as Anderson-Fabry disease (AFD). HCM carries a risk of sudden cardiac death (SCD) of 0.9%/year, and is the most common cause of SCD in young adults. Recent studies suggested Mechanical Dispersion (MD) by Speckle-Tracking Echocardiography (STE) as an additional arrhythmic risk marker, even despite preserved ejection fraction. We aimed to assess the incremental prognostic value of global longitudinal strain (LV-GLS) and MD in HCM or AFD patients for ventricular arrhythmias.
Novel echocardiographic predictors for arrhythmic risk stratification in Hypertrophic Cardiomyopathies
Margherita stefania Rodolico;
2022
Abstract
Hypertrophic Cardiomyopathies are caused in 60% by mutations in cardiac sarcomere genes (HCM), but also include metabolic diseases, such as Anderson-Fabry disease (AFD). HCM carries a risk of sudden cardiac death (SCD) of 0.9%/year, and is the most common cause of SCD in young adults. Recent studies suggested Mechanical Dispersion (MD) by Speckle-Tracking Echocardiography (STE) as an additional arrhythmic risk marker, even despite preserved ejection fraction. We aimed to assess the incremental prognostic value of global longitudinal strain (LV-GLS) and MD in HCM or AFD patients for ventricular arrhythmias.File in questo prodotto:
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