The hydroformylation and the tandem hydroformylation-reductive amination reactions have been applied first time on solid phase. The work demonstrates that the cited reactions can be carried out successfully on terminal alkenes supported on PS-DVB resins with classsical trityl or Wang linkers. The application of this tecnology is the preparation of libraries of small organic molecules and natural like compounds.
Hydroformylation of Terminal Alkenes Supported on Solid Phase. A New Synthetic Tool for Combinatorial Chemistry
Mauro Marchetti;
2003
Abstract
The hydroformylation and the tandem hydroformylation-reductive amination reactions have been applied first time on solid phase. The work demonstrates that the cited reactions can be carried out successfully on terminal alkenes supported on PS-DVB resins with classsical trityl or Wang linkers. The application of this tecnology is the preparation of libraries of small organic molecules and natural like compounds.File in questo prodotto:
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