Glycoproteins have a fundamental role in many physiological and pathological processes. Glycopeptides, which retain the critical carboydrate-peptide linkage region of a glycoprotein, are much more amenable to study and are important models for glycoproteins. Strategy for generating glycopetide mimics with non-native sugar-peptide linkages have been recently described which use chemoselective ligation.
Recent progress in glycopeptide synthesis
Gobbo M
2003
Abstract
Glycoproteins have a fundamental role in many physiological and pathological processes. Glycopeptides, which retain the critical carboydrate-peptide linkage region of a glycoprotein, are much more amenable to study and are important models for glycoproteins. Strategy for generating glycopetide mimics with non-native sugar-peptide linkages have been recently described which use chemoselective ligation.File in questo prodotto:
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