The iodine-magnesium exchange reaction allows the preparation of polyfunctional aryl, heteroaryl, or alkenyl magnesium reagents at low temperature. These reagents display the typical reactivity of Grignard compounds and undergo various copper-catalyzed reactions such as allylation or 1,4-addition. Using this halogen -metal exchange reaction, it was possible to generate polyfunctional magnesium reagents on the solid phase.
New polyfunctional magnesium reagents for organic synthesis
Varchi G.Writing – Review & Editing
;
2000
Abstract
The iodine-magnesium exchange reaction allows the preparation of polyfunctional aryl, heteroaryl, or alkenyl magnesium reagents at low temperature. These reagents display the typical reactivity of Grignard compounds and undergo various copper-catalyzed reactions such as allylation or 1,4-addition. Using this halogen -metal exchange reaction, it was possible to generate polyfunctional magnesium reagents on the solid phase.File in questo prodotto:
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