Recently, the exhaled breath temperature has been proposed as a potential marker for the evaluation of airway inflammation in asthma. The purpose of this study was to verify the ability to distinguish asthmatics from normal controls by a dedicated detailed mathematical evaluation of the exhaled air curve. Analysis was performed in the different phases of the curve of exhaled temperature, i.e. the rate of temperature increase (DeT) and the mean plateau value. Principal components analysis (PCA) and artificial neural networks (ANNs) were used for the evaluation of the data in 90 asthmatic children and in 33 healthy age-matched controls. Both PCA and ANNs showed that a separation between patients and controls can be obtained only by the evaluation of the plateau phase of the curve, which better reflects the periphery of the airway.
Exhaled air temperature in asthmatic children: a mathematical evaluation
Pioggia G;Ferro M;
2009
Abstract
Recently, the exhaled breath temperature has been proposed as a potential marker for the evaluation of airway inflammation in asthma. The purpose of this study was to verify the ability to distinguish asthmatics from normal controls by a dedicated detailed mathematical evaluation of the exhaled air curve. Analysis was performed in the different phases of the curve of exhaled temperature, i.e. the rate of temperature increase (DeT) and the mean plateau value. Principal components analysis (PCA) and artificial neural networks (ANNs) were used for the evaluation of the data in 90 asthmatic children and in 33 healthy age-matched controls. Both PCA and ANNs showed that a separation between patients and controls can be obtained only by the evaluation of the plateau phase of the curve, which better reflects the periphery of the airway.| Campo DC | Valore | Lingua |
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| dc.authority.ancejournal | PEDIATRIC ALLERGY AND IMMUNOLOGY | - |
| dc.authority.orgunit | Istituto di Fisiologia Clinica - IFC | - |
| dc.authority.people | Pifferi M | it |
| dc.authority.people | Ragazzo V | it |
| dc.authority.people | Previti A | it |
| dc.authority.people | Pioggia G | it |
| dc.authority.people | Ferro M | it |
| dc.authority.people | Macchia P | it |
| dc.authority.people | Piacentini GL | it |
| dc.authority.people | Boner AL | it |
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| dc.date.accessioned | 2024/02/20 06:24:08 | - |
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| dc.date.issued | 2009 | - |
| dc.description.abstracteng | Recently, the exhaled breath temperature has been proposed as a potential marker for the evaluation of airway inflammation in asthma. The purpose of this study was to verify the ability to distinguish asthmatics from normal controls by a dedicated detailed mathematical evaluation of the exhaled air curve. Analysis was performed in the different phases of the curve of exhaled temperature, i.e. the rate of temperature increase (DeT) and the mean plateau value. Principal components analysis (PCA) and artificial neural networks (ANNs) were used for the evaluation of the data in 90 asthmatic children and in 33 healthy age-matched controls. Both PCA and ANNs showed that a separation between patients and controls can be obtained only by the evaluation of the plateau phase of the curve, which better reflects the periphery of the airway. | - |
| dc.description.affiliations | Department of Pediatrics, University of Pisa, Pisa; Interdepartmental Research Center ``E. Piaggio'', Faculty of Engineering, University of Pisa - Institute of Clinical Physiology CNR; Department of Pediatrics, University of Verona, Verona, Italy | - |
| dc.description.allpeople | Pifferi, M; Ragazzo, V; Previti, A; Pioggia, G; Ferro, M; Macchia, P; Piacentini, Gl; Boner, Al | - |
| dc.description.allpeopleoriginal | Pifferi M, Ragazzo V, Previti A, Pioggia G, Ferro M, Macchia P, Piacentini GL, Boner AL. | - |
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| dc.identifier.doi | 10.1111/j.1399-3038.2008.00742.x | - |
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| scopus.description.abstracteng | Pifferi M, Ragazzo V, Previti A, Pioggia G, Ferro M, Macchia P, Piacentini GL, Boner AL. Exhaled air temperature in asthmatic children: a mathematical evaluation. Pediatr Allergy Immunol 2009: 20: 164-171. © 2008 The Authors Journal compilation © 2008 Blackwell Munksgaard Recently, the exhaled breath temperature has been proposed as a potential marker for the evaluation of airway inflammation in asthma. The purpose of this study was to verify the ability to distinguish asthmatics from normal controls by a dedicated detailed mathematical evaluation of the exhaled air curve. Analysis was performed in the different phases of the curve of exhaled temperature, i.e. the rate of temperature increase (e°T) and the mean plateau value. Principal components analysis (PCA) and artificial neural networks (ANNs) were used for the evaluation of the data in 90 asthmatic children and in 33 healthy age-matched controls. Both PCA and ANNs showed that a separation between patients and controls can be obtained only by the evaluation of the plateau phase of the curve, which better reflects the periphery of the airway. © 2008 Blackwell Munksgaard. | * |
| scopus.description.allpeopleoriginal | Pifferi M.; Ragazzo V.; Previti A.; Pioggia G.; Ferro M.; MacChia P.; Piacentini G.L.; Boner A.L. | * |
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| Appare nelle tipologie: | 01.01 Articolo in rivista | |
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