This book presents a collection of chapters dealing with the latest developments in CA research, which has experienced an important revival in the last 5 years, with the discovery of several classes of inhibitors and their mechanisms of action, as well as the validation of some human CA isoforms as antitumor/antimetastatic drug targets. Indeed, sulfonamide/sulfamate CA inhibitors are clinically used as diuretics, antiglaucoma, antiepileptic and antiobesity agents.
Targeting carbonic anhydrases
Capasso C.
2014
Abstract
This book presents a collection of chapters dealing with the latest developments in CA research, which has experienced an important revival in the last 5 years, with the discovery of several classes of inhibitors and their mechanisms of action, as well as the validation of some human CA isoforms as antitumor/antimetastatic drug targets. Indeed, sulfonamide/sulfamate CA inhibitors are clinically used as diuretics, antiglaucoma, antiepileptic and antiobesity agents.File in questo prodotto:
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