Polysaccharides such as hyaluronic acid and β-cyclodextrins thanks to their biocompatibility, accessibility, and biological and technological properties are widely employed in several biomedical/pharmaceutical applications. Moreover, their ability to act as stabilizers towards metal nanoparticles has been recently investigated [1-3]. Here, we describe a new synthetic strategy for the preparation of hyaluronic acid β-cyclodextrin (HA-CD) conjugate and its ability to interact with iron nanoparticles (SPIONS) and gold nanoparticles (Au NPS) producing new hybrid glyco-materials for theranostic applications.
Innovative Hybrid Nano-Architectures based on Cyclodextrin-Hyaluronic Acid Bioconjugate and Metal Nanoparticles
Mazzaglia A;
2023
Abstract
Polysaccharides such as hyaluronic acid and β-cyclodextrins thanks to their biocompatibility, accessibility, and biological and technological properties are widely employed in several biomedical/pharmaceutical applications. Moreover, their ability to act as stabilizers towards metal nanoparticles has been recently investigated [1-3]. Here, we describe a new synthetic strategy for the preparation of hyaluronic acid β-cyclodextrin (HA-CD) conjugate and its ability to interact with iron nanoparticles (SPIONS) and gold nanoparticles (Au NPS) producing new hybrid glyco-materials for theranostic applications.File in questo prodotto:
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