The interaction of phosphatidylcholine liposomes used as cell models, with cationic liposomes formulated with 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine and amphiphiles based on a pyrrolidinium headgroup was investigated by differential scanning calorimetry and fluorescence resonance energy transfer experiments. The results obtained showed that subtle variations in the formulation can influence lipid interactions and were correlated to a previous biological evaluation.

Interaction of cationic liposomes with cell membrane models

L Giansanti;G Mancini
2011

Abstract

The interaction of phosphatidylcholine liposomes used as cell models, with cationic liposomes formulated with 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine and amphiphiles based on a pyrrolidinium headgroup was investigated by differential scanning calorimetry and fluorescence resonance energy transfer experiments. The results obtained showed that subtle variations in the formulation can influence lipid interactions and were correlated to a previous biological evaluation.
2011
Istituto per i Sistemi Biologici - ISB (ex IMC)
Cationic liposomes
Differential scanning calorimetry
fluorescence resonance energy transfer
Fusion
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/49945
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact