Extracellular Vesicles: Diagnostic and Therapeutic Applications in Cancer

Extracellular vesicles represent a heterogeneous family of lipid bilayer-enclosed particles naturally released by all cytotypes into the extracellular space. They can act as mediators of cell–cell communication. Recently, the applications of extracellular vesicles (EVs) have been of great interest in translational cancer research. The advances in next-generation omics technologies allow us to discover EVs’ selective cargo packaging and as EV roles in horizontal transport, non-invasive biomarkers, and as new therapeutic options. Herein, discussing recent studies, information on extracellular vesicle (EV) biogenesis, morphological characteristics, isolation, and current detection methods is summarized.