We identified associations at the MAPT, APOE, and MOBP loci with FTD, suggesting potential common genetic denominators across multiple neurological conditions (i.e., FTD, PSP, ALS, AD, PD, and CBD). These findings will aid in the further characterization of the common and disease-specific pathogenesis of, and interventions for, these disorders.
Genome-wide analyses reveal a potential role for the MAPT, MOBP, and APOE loci in sporadic frontotemporal dementia
emilia vitale
2024
Abstract
We identified associations at the MAPT, APOE, and MOBP loci with FTD, suggesting potential common genetic denominators across multiple neurological conditions (i.e., FTD, PSP, ALS, AD, PD, and CBD). These findings will aid in the further characterization of the common and disease-specific pathogenesis of, and interventions for, these disorders.File in questo prodotto:
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