Sleep disorders affect the majority of ALS and DM1 patients. Home cage monitoring (HCM) is a suitable tool to screen and evaluate abnormal sleep behavior in mouse models of neurodegenerative diseases. The automated, long-term, non-invasive nature of HCM is cruciall when assessing mice with a progressive and severe phenotype.

Home cage monitoring uncovers sleep-related phenotypes in mouse models of ALS and DM1

silvia mandillo
Conceptualization
2024

Abstract

Sleep disorders affect the majority of ALS and DM1 patients. Home cage monitoring (HCM) is a suitable tool to screen and evaluate abnormal sleep behavior in mouse models of neurodegenerative diseases. The automated, long-term, non-invasive nature of HCM is cruciall when assessing mice with a progressive and severe phenotype.
2024
Istituto di Biochimica e Biologia Cellulare - IBBC - Sede Secondaria Monterotondo
home cage monitoring, mouse phenotyping, sleep disorders
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.14243/521464
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